No. There have been odd theories like Mogi donuts, in which a lack of earthquakes at some distances was thought to suggest danger, but they are out of fashion now. Generally, more earthquakes are thought to cause or signal a higher chance of a future earthquakes, a lack of earthquakes the opposite.

M5 earthquakes don't contribute nearly enough energy release to unload faults, so a lack of 5s does not mean the faults are any more loaded than if more 5s occurred.